Conformational flexibility and structural variability of SARS-CoV2 S protein

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of expression and titration of recombinant nucleocapsid protein as an immunogenic candidate against SARS-CoV2

Introduction: Covid-19 epidemic results from an infection caused by SARS-CoV2. Evolution-based analyses on the nucleotide sequences show that SARS-CoV2 is a member of the genus Beta-coronaviruses and its genome consists of a single-stranded RNA, encoding 16 proteins. Among the structural proteins, the nucleocapsid is the most abundant protein in virus structure, highly immunogenic, with sequenc...

متن کامل

SARS‐CoV2 Neuroinvasion Potential; Narrative Review

The outbreak of severe acute respiratory syndrome (SARS ‐ CoV-2) in December 2019 has led to the epidemic of Covid-19. Recent clinical studies have shown that parts of the nervous system; Cerebrospinal fluid (CSF) are involved in SARS-CoV-2 infection, which is associated with a variety of neurological manifestations such as headache, dizziness, and olfactory and gustatory disorders. This study ...

متن کامل

MolMovDB: analysis and visualization of conformational change and structural flexibility

The Database of Macromolecular Movements (http://MolMovDB.org) is a collection of data and software pertaining to flexibility in protein and RNA structures. The database is organized into two parts. Firstly, a collection of 'morphs' of solved structures representing different states of a molecule provides quantitative data for flexibility and a number of graphical representations. Secondly, a c...

متن کامل

Intrauterine Vertical Transmission of SARS COV2 Infection in Iranian Neonates

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) is responsible for COVID-19 disease that is transmitted from human to human via respiratory droplets and contact routes. There is no clear accurate evidence about intrauterine transmission of COVID-19 infection among newborns. Case present :The present report aims at provid ing accurate and clear information about a one-day singleton...

متن کامل

Protein Conformational Flexibility Analysis with Noisy Data

Protein conformational changes play a critical role in biological functions such as ligand-protein and protein-protein interactions. Due to the noise in structural data, determining salient conformational changes reliably and efficiently is a challenging problem. This paper presents an efficient algorithm for analyzing protein conformational changes, when the data is noisy. It applies a statist...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Structure

سال: 2021

ISSN: 0969-2126

DOI: 10.1016/j.str.2021.04.006